Tmem192-ha
WebTMEM192 is a widely expressed, four transmembrane protein that localizes to late endosomal/lysosomal membranes. This localization is mediated by two dileucine motifs present at the amino-terminus of TMEM192. A cysteine residue near the carboxy residue is responsible for disulfide bond formation in TMEM192 homodimers. Little is known about … WebTmem192 Constitutive Knockout. start an order print this page share this page. Inquire. CALL: 888.822.6642 + 45 70 23 04 05 (EUROPE and DENMARK) +49 214 50 68 023 …
Tmem192-ha
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Webtagged TMEM192 (Control-Lyso cells) or 3xHA-tagged Tmem192 (HA-Lyso cells). ER, endoplasmic reticulum. ( Dto F) Purified lysosomes are intact and retain their contents. (D) Cathepsin D activity was measured in whole-cell lysates and lysosomes, and immunoprecipitates from Control-Lyso cells served as a negative control (Control IP) … WebApr 6, 2024 · This initial TFEB-independent recovery of hydrolase activity may be explained by previous reports that demonstrated that 1 mM LLOMe treatment for 2 h causes …
WebApr 12, 2024 · (J–L) (J) Schematic description, (K) immunoblot, and (L) quantification of lysosome ESCRT components by anti-HA immunoprecipitation (LysoIP; TMEM192-3xHA) from HeLa ATG5-WT and HeLa ATG5-KO cells treated as in (F). Long exp (long exposure) and Short exp (short exposure) correspond to the same blot. Data, mean ± SE (n = 3); two … WebOur TMEM219 polyclonal antibodies are developed in Rabbit and Sheep. Find the TMEM219 antibody that fits your needs. Choose from 1 of 2 TMEM219 antibodies, which have been …
WebJul 27, 2024 · J. Representative immunofluorescence staining of ER (CLIMP63, green) and lysosomes (TMEM192-HA, red) in FGFR3;4KO chondrocytes treated with vehicle (5% ABS) and FGF18 ( 50 ng/ml for 16 h). BafA1 was used at 100 nM for 4 h to inhibit lysosomal degradation. Quantification of relative CLIMP63 fluorescence into TMEM192-HA-positive … WebOct 16, 2024 · As a control, we determined expression of FLAG-EEA1 in the context of TMEM192 HA and found it had little effect on the abundance of ~6000 proteins based on total proteome analysis using TMT when ...
WebReceptors for this type of autophagy (aggrephagy) include p62, NBR1, TOLLIP, and OPTN, which possess LC3-interacting regions and ubiquitin-binding domains (UBDs), thus working as a bridge between LC3/GABARAP proteins and ubiquitinated substrates. interview went badlyWebApr 21, 2024 · TMEM192-3×HA is a significant improvement over earlier attempts at this strategy, where the lysosome-associated membrane protein 1 (LAMP1) fused to a … interview went well but haven\u0027t heard backWebMar 18, 2024 · In brief, TMEM192-HA and TMEM192-FLAG cells were grown in the presence of BafA1 (200 nM, 2 h), washed twice in PBS, scraped off and transferred to tubes on ice. … new haven ct weather year roundWebSep 21, 2024 · TMEM192–3×HA marks lysosomes with a triple HA epitope, enabling their immunoisolation with anti-HA antibodies. Immunofluorescence-based analyses of liver and brain sections, two tissues... new haven ct waterfrontWeb胎牛血清（杂交瘤细胞专用） sp2/0 小鼠骨髓瘤细胞. 佐剂乳化器 new haven ct weather forecast 5 dayWebDisclosed herein are methods and compositions for modulating MFSD12 expression and activity to treat diseases such as lysosomal storage diseases, including cystinosis. Also disclosed are methods of altering skin pigmentation and methods of screening for MFSD12 modulation agents. interview welcome scriptWebYour search returned 97 TMEM192 Western Blot Antibodies across 21 suppliers. Showing 21 of 21 suppliers (97 products total) > >> Select All. Select up to 5 products from below to compare or request more information. Request Info for all products Compare. Sponsored Products MyBioSource.com TMEM192 Antibody ... interview well but no job offer