WebApr 9, 2024 · Polygenic hypercholesterolemia is the most common cause of elevated serum cholesterol concentrations. Low-density lipoprotein cholesterol (LDL-C) elevations are moderate (140-300 mg/dL) with serum triglyceride concentrations within the reference range. However, practically speaking, the material in this article is also relevant to patients … WebOct 3, 2024 · The rising burden of cardiovascular diseases (CVDs) and projected mortality of about 4 million people by 2030 have posed a big public health threat. 1, 2 The Framingham Heart Study has demonstrated a direct relationship between the serum cholesterol levels and CVD such as coronary heart disease (CHD) and stroke. 3, 4 As per an estimate by the …
[CME: Primary and Secondary Hypercholesterolemia]
WebFor primary prevention of CVD, it is recommended to use a systematic strategyto identify people at high risk (e.g. the NHS Health Check programmeand pending CVD Prevention Audit[Quick Guide to CVDPREVENT.pdf]). NICE defines high risk as an estimated CVD risk of 10% or more over 10 years. WebJan 1, 2010 · Serum lipids can be raised in association with several diseases, such as hypothyroidism and nephrotic syndrome (secondary hyperlipidaemia). Hypercholesterolaemia or hypertriglyceridaemia may also be primary, probably genetic. Fredrickson (1967) classified and... granite alternative group
Summary of National Guidance for Lipid Management for Primary …
WebObjective Familial hypercholesterolaemia (FH) is characterised by elevated low-density lipoprotein (LDL)-cholesterol and increased risk of cardiovascular disease. However, FH remains substantially underdiagnosed and undertreated. We employed a two-stage pragmatic approach to identify and manage patients with FH in primary healthcare. … WebPotential secondary causes of hypercholesterolaemia (diabetes, hypothyroidism, steroid use, renal and liver disease) should be excluded before FH is further assessed. 3 Personal or family history of premature CAD and markedly elevated cholesterol levels, both central to the Dutch Lipid Clinic Network Criteria (DLCNC) score, are the chief drivers for establishing a … WebOct 1, 2024 · Current Literature. In patients age 75 and younger, the efficacy of statins for primary prevention is well-established on the basis of multiple randomized trials, which have found that they reduce the relative risk of major vascular events by 20-30%. 2,3 Given the paucity of adults >70 years in clinical trials, the evidence for the efficacy of ... granite alaskan white