2024 Primary platinum refractory disease

Primary platinum refractory disease

Author: aojf

August undefined, 2024

Web1 day ago · In patients with platinum-refractory disease, the ORR was 13.2% with the combination and 18.3% with nivolumab alone. Source: Getty Images Compared with nivolumab alone, ipilimumab plus nivolumab ... WebJan 23, 2024 · Among the 94 patients with high-grade serous ovarian cancer who received treatment in this study, 11 (12%) had primary platinum-refractory disease, an understudied subpopulation with a substantially worse prognosis. For this reason, as was the case in …

Relacorilant Plus Nab-Paclitaxel Extends Survival in Women

WebMar 14, 2024 · Forty percent of the women had suboptimally resected stage III disease, and 26% had stage IV disease. The primary end point of the study was PFS.[Level of evidence B1] ... Responses have been observed … WebJun 23, 2016 · Patients were categorized as PPR (disease progression <6 months after completing first-line platinum therapy) or SPR (progression ≥6 months after first platinum … cost for a chick fil a franchise

Adding Ipilimumab to Nivolumab Provides No Benefit in Recurrent …

WebMar 31, 2024 · When excluding those with primary platinum-refractory disease and those who previously received 4 or more lines of therapy, intermittent relacorilant plus nab … WebJan 31, 2024 · The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. … WebMar 30, 2024 · Excluding women with primary platinum-refractory disease and patients who had received four or more prior lines of treatment, women in the intermittent arm … breakfast on the go apartments

Overall Survival Increased Among Patients With Recurrent …

Efficacy and Safety of Mirvetuximab Soravtansine in Patients With ...

WebSep 6, 2013 · Primary platinum-resistant: Previously untreated patients who have achieved at least a partial response to platinum-based chemotherapy but experience a relapse … cost for a chimneyWebDisease status just prior to the start of the preparative regimen for hematopoietic stem cell transplantation (HSCT): Primary refractory refers to never achieving a complete … cost for a chimney sweep

"WebPrior to the advent of PD1/PDL1 checkpoint inhibitors, systemic chemotherapy with cisplatin-based regimens was the standard of care, leading to median survival of around 1 year. 5,6 For patients with platinum-refractory disease, the median survival was only 6–9 months. 7–10 Furthermore, up to 30%–50% of patients with metastatic UC are ineligible … " - Primary platinum refractory disease

Primary platinum refractory disease

Clinical Challenges: Platinum-Resistant Ovarian Cancer

WebAbstract. Purpose: In general, 50 % up to 80 % of metastasized germ cell tumor patients can be cured by platinum-based chemotherapy. However, 3-5 % of patients will still die of … http://pubs.sciepub.com/jcrt/4/2/3/jcrt-4-2-3.pdf

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WebDec 1, 2024 · Relapsed lymphoma is a disease that responded to treatment initially, but then returned. Refractory disease means the cancer hasn’t responded to the initial treatment … WebJan 23, 2024 · Whereas the majority of patients show at least a partial response to these therapies (resulting in median overall survival of 4.3 years [2]), 25% will be platinum-refractory in the primary setting ...

WebJan 31, 2011 · CathyAsh. Jan 31, 2011 • 10:40 AM. Here's my understanding: Platinum refractory: cancer grew while on platinum therapy. Platinum resistant: recurrance within 6 … WebDec 4, 2024 · The mean number of prior lines of chemotherapy was 1.3 which mean almost all of had primary platinum-refractory diseases. Median treatment duration was 4.3 months (1.1~16.1).

WebMar 22, 2024 · However, those with primary platinum-refractory disease were excluded. The primary end point of the study was confirmed objective response rate (ORR) as assessed by investigators with a key secondary end point of duration of response (DOR). ORR was also assessed by a blinded independent central review (BICR). WebStandard treatment for ovarian cancer is platinum-based chemotherapy; however, 15% to 30% of patients with ovarian cancer have primary platinum-resistant or refractory …

WebJun 14, 2024 · However, excluding patients with primary platinum-refractory disease did reveal a statistically significant difference in median OS, indicating limited effects in the …

WebOct 25, 2024 · Patient has primary platinum-refractory disease or primary platinum resistance, defined as disease progression during first-line platinum-based therapy … cost for a company to install gymWebSep 26, 2024 · Patients with primary platinum-refractory disease as defined by those who progressed during or within four weeks of completion of first platinum-based … cost for a concrete walkwayWeb•Patietnts with primary platinum-refractory disease (defined as progression during or within 4 weeks after completion of the first platinum regimen) are not eligible. • EOG of 0 to 1. • … breakfast on the go flyer templateWebOct 26, 2024 · If patients had primary platinum-refractory disease or primary platinum resistance, a histologically confirmed diagnosis of epithelial ovarian carcinoma with … cost for acre of land in pennsylvaniaWebThe primary endpoint of the study was treatment failure-free survival ... Single-agent nab-paclitaxel was well tolerated and demonstrated efficacy in advanced NSCLC patients with … cost for a condo water heaterWebpatients with platinum resistant ovarian cancer. Patients with platinum resistant ovarian carcinoma and measurable disease received canfosfamide at 960 mg/m2 in combination with PLD at 50 mg/m2, intravenously day 1 in every 28 day cycles until tumor progression or unacceptable toxicities. The primary endpoints were objective response cost for acl surgery dogWebJun 8, 2024 · When patients with primary platinum-refractory disease were excluded from the analysis, intermittent dosing was associated with significantly improved OS (median … breakfast on the go cereal