Perinuclear dot-like staining pattern
WebNov 15, 2012 · Studies demonstrate that CD99 positive cells show paranuclear dot-like immunoreactivity in PC [40] [41] [42]. In addition, pancreatic solid-pseudopapillary neoplasms show an exclusive dot-like... Webing perinuclear cytokeratin dots is small cell carci-noma. Typically in this tumor, the dots are relative-ly small, and in nearly all cases, these cytokeratin dots are more prominent with …
Perinuclear dot-like staining pattern
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WebSpectrins are a family of cytoskeletal proteins that organize and link membranes to subcellular motors and filaments. Although traditionally divided into erythroid and non-erythroid forms, the discovery of new spectrin isoforms in various tissues indicates that their distribution is not yet fully characterized. To our knowledge, there is no comprehensive … WebAug 29, 2024 · This dual stain has 2 additional diagnostic uses: cytoplasmic staining for WT1 is characteristic of melanoma and some sarcomas, 8 and AE1/AE3 demonstrates a weak, perinuclear “dot-like” pattern in small cell carcinoma. 9 In the majority of cases, this stain is sufficient on its own to differentiate mesothelial from epithelial cells, and to …
WebWe present a case of EFH with dot-like Golgi pattern perinuclear ALK expression, a previously undescribed staining pattern. We surmised this unique staining pattern could be due to a novel fusion partner, and using FISH, we confirmed a rearrangement of the ALK (2p23) locus. Further investigation with whole transcriptome sequencing led to the ... WebPseudoverrucous papules and nodules are a skin condition characterized by striking 2– to 8–mm, shiny, smooth, red, moist, flat-topped, round skin lesions in the perianal area of …
WebOne reported case with minimal desmoplasia was negative for WT1 and CD99 and had only 5% staining with EMA and patchy weak desmin staining with "scanty" perinuclear dot-like positivity [26 ... WebJan 7, 2024 · We aimed to determine the significance of cytoplasmic antinuclear antibody (ANA) patterns using computer-aided immunofluorescence microscopy in patients with autoimmune liver diseases (AILD). ANA staining pattern was identified by treating cultured human epithelial type 2 (HEp-2) cells with the sera of the patients. Medical records of …
WebBackground: Recent reviews have referred to the paranuclear dot-like staining pattern of CD99 in several neoplasms, including solid pseudopapillary tumors in the pancreas, …
WebCK20 staining showing the characteristic perinuclear dot-like positivity Source publication +3 Merkel cell carcinoma: A review and update on aetiopathogenesis, diagnosis and treatment... how old to use draft kingsmeri brown and kody splitWebn of immunohistochemical expression of ALK in EFH in the literature thus far describes both granular cytoplasmic staining and nuclear staining. We present a case of EFH with dot-like Golgi pattern perinuclear ALK expression, a previously undescribed staining pattern. We surmised this unique staining pattern could be due to a novel fusion partner, and using … how old to use etoroWebMar 1, 2024 · MUC5AC expression in ALK + cancers was exclusively visualized through cytoplasmic staining (100%), whereas EGFR-mutated cancers showed predominantly perinuclear dot-like patterns (90.5%) and focal cytoplasmic staining (9.5%). MUC2 and MUC6 expression was not detected in either type of lung cancer. meri brown banana bread recipeWebMay 19, 2015 · The Topo I-like pattern can comprise staining of five subcellular regions: 1) Prominent fine speckled nuclear staining in interphase cells. 2) Consistent strong fine speckled staining of condensed chromatin in mitotic cells. Depending on the serum dilution used, the mitotic chromatin staining may appear homogeneous. meri brown catfish arrestWebThe peculiar perinuclear dot-like staining pattern for vimentin and desmin is characteristic for DSRCT. EWS-WT1 fusion transcript can be detected in formalin-fixed, paraffin-embedded tissue by RT-PCR, which may thus serve as a useful diagnostic adjunct for DSRCT. MeSH terms Abdominal Neoplasms / diagnostic imaging Abdominal Neoplasms / metabolism how old to use gymWebApr 14, 2024 · adjective. peri· nu· cle· ar -ˈn (y)ü-klē-ər. : situated around or surrounding the nucleus of a cell. perinuclear structures. how old to use fanduel sportsbook