Tīmeklis2024. gada 19. febr. · 巨噬细胞 是一种多用途且分布广泛的白细胞，存在于人体的许多（不是全部）组织中。 是单核吞噬细胞系统的一部分，其主要发现的作用是吞噬死 … TīmeklisFizz1 (resistin-like-α)、抑炎因子IL-10 (interleukin-10)、 TGF-β (transforming growth factor-β)，以及特异性 地表达更高水平的甘露糖受体 (mannose receptor, MRC1)，还能生成胶原质以促进组织修复[7]。随着 研究发现不同环境下巨噬细胞具有可塑性，逐渐确
M1和M2型巨噬细胞表型的比较分析 - 豆丁网
Tīmeklis2012. gada 13. dec. · 最早的体内和体外实验均证实IL-4可调控FIZZ1在巨噬细胞中的表达，并与其替代激活途径有关。 后相继发现FIZZ1基因组序列中存在核因子κB、CAAT/增强子结合蛋白（C/EBP）、信号转导和转录激活因子6（STAT6）等转录因子结合位点，提示FIZZ1可能受这些因子的调节。 在对过敏性肺炎研究中发现FIZZ1是炎症初期诱导 … TīmeklisFurthermore, we demonstrate that the in vivo induction of FIZZ1 and Ym1 in macrophages depends on IL-4 and that in vitro, IFN-gamma antagonizes the effect of IL-4 on the expression of FIZZ1 and Ym1. Collectively, these results open perspectives for new insights into the functional properties of aaMphi and establish FIZZ1 and Ym1 … teamvyanet myhub intranet
除经典的M1、M2巨噬之外，还有肿瘤相关巨噬细胞(TAM) …
Tīmeklis2000. gada 1. aug. · Generation of anti-FIZZ1 antibody. Rabbit polyclonal antibody to mouse FIZZ1 was generated using the peptide ENKVKELLANPANYP coupled to keyhole limpet hemocyanin. The antigen was injected in complete Freund's adjuvant and boosted every 3 weeks. Post-immune serum samples collected 1 week after each … TīmeklisThe mRNA levels of interleukin (IL)-6, IL-1β, and NOS2 as M1 markers were significantly decreased while those of select M2 markers such as Arg-1, FIZZ1, and YM-1 were significantly enhanced. It was also observed that aryl hydrocarbon receptor (AhR) signaling was significantly increased during asthma pathogenesis as demonstrated … http://www.nwbiotec.com/index.php?g=&m=Article&a=new_nav_list&newid=507 team vvcs