WebJun 23, 2016 · Crystallopathies. To the Editor: Mulay and Anders (June 23 issue) 1 describe the mechanisms of interactions between crystals and the inflammasome-mediated innate … WebDisease Entity. West African Crystalline Maculopathy (WACM) Disease. West African Crystalline Maculopathy is an asymptomatic, asymmetric, bilateral or unilateral crystalline maculopathy characterized by focal …
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WebSep 29, 2016 · N Engl J Med. 2016 Sep 29;375(13):e29. doi: 10.1056/NEJMc1609332. Authors Shrikant R. Mulay, Hans-Joachim Anders hudson new york resorts
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Crystallopathy is a harmful state or disease associated with the formation and aggregation of crystals in tissues or cavities, or in other words, a heterogeneous group of diseases caused by intrinsic or environmental microparticles or crystals, promoting tissue inflammation and scarring. See more Crystallopathies can be associated with four main kinds of crystalline structures: liquid non-aggregating crystal solutions, amorphous nano-scale solid particles, crystalline micro-scale solid particles, and polycrystalline … See more Local supersaturation is a common trigger of crystallization, and when the nucleus of the crystalline structure is formed, crystals can self-perpetuate … See more In principle, crystal formation can happen anywhere in the body. Well-known places are excretory organs where concentrations get high easily, like in the biliary and urinary tracts, but crystalline structures are also formed in intracellular and extracellular spaces of tissues, … See more The most straightforward treatment of crystallopathies would be dissolving the crystals. Crystal dissolvents have been under research, for example with cyclodextrin in atherosclerosis. Another approach would be to modify the inflammatory … See more WebMar 5, 2024 · PD-1/PD-L1 inhibitors such as pembrolizumab have radically improved the prognosis for many patients with advanced malignancies. Although revolutionary, its use can be complicated and limited by various immune-related adverse effects. Effective management depends on early recognition and prompt intervention. Herein, we describe … Web→ glyoxylate, hyperoxalurie, cristallopathie néphropathie amyloïde l.f. → amylose rénale néphropathie avec perte de sel l.f. salt losing nephritis Altération rénale marquée [dictionnaire.academie-medecine.fr] holding hostage images