WebAtorvastatin merupakan antihiperlipidemia golongan statin dan termasuk BCS (Biopharmaceutical Class System) kelas II yang memiliki permeabilitas tinggi dan kelarutan yang rendah. Kelarutan zat aktif dalam air yang rendah menghasilkan laju disolusi dan bioavailabilitas yang rendah sehingga berpengaruh pada efektifitas terapinya. Oleh … WebMar 8, 2024 · Anda perlu menemukan keterampilan Anda yang dapat dialihkan, merencanakan jurnal karier, tidak meremehkan keterampilan lunak Anda, dan mencari seorang mentor. Penelitian dan studi tentang perencanaan suksesi saat ini menetapkan bahwa menentukan tujuan dan sasaran posisi kepemimpinan sangat penting dalam …
Perencanaan Karir dan Perencanaan Suksesi ( Karier) …
WebApr 15, 2024 · Atorvastatin is a widely used statin drug that prevents cardiovascular disease and treats hyperlipidemia. The major metabolites in humans are 2-OH and 4-OH atorvastatin, which are active metabolites known to show highly inhibiting effects on 3-hydroxy-3-methylglutaryl-CoA reductase activity. Producing the hydroxylated metabolites … WebThe separation was achieved from C18 In vitro drug diffusion studies: In vitro diffusion column ( 5µ, 4.6 X 150 mm, Waters, USA) at 25 ºC studies were carried out for brand A and D. Atorvastatin temperature with a mobile phase comprising of solution in methanol and atorvastatin dispersed in water Bangladesh Pharmaceutical Journal Vol. 14, No ... atta kim
Influence of Preparation Methods on Physicochemical and …
WebApr 6, 2024 · A highly selective, sensitive, rugged, and rapid ultra high-performance liquid chromatography-tandem mass spectrometry method (UPLC-MS/MS) is optimized and validated for reliable quantification of atorvastatin (ATR) and its active metabolites, 2-hydroxy atorvastatin (2-ATR) and 4-hydroxy atorvastatin (4-ATR) in human plasma … WebHubungan Dosis dan Durasi Pemberian Atorvastatin Terhadap Outcome Terapi Pasien Penyakit Jantung Koroner Ririn Wirawati1 1Program Studi farmasi, Universitas PGRI … WebA two way, randomized cross-over bioequivalence study was conducted to analyse the rate and extent of absorption of atorvastatin after a single dose of 80 mg atorvastatin as atorvastatin calcium tablets. The study was carried out using healthy male volunteers (N = 24). A high performance liquid chro … atta ki chakki russia